Understanding Breast Cancer Genetics

This is a wonderfully well written book in concise form for easy reading.The content is as up to date, as anyone can wish, containing all the latest information on the genetics of breast cancer not easily found in other publications.I have already found it extremely useful and have referred to it in lectures to doctors and medical students.


Understanding Breast Cancer Genetics

Pancreatic Cancer

Description: Since the previous M.D. Anderson Solid Tumor Oncology Series publication on pancreatic cancer, there have been major advances in our understanding of molecular events which underlie pancreatic cancer development, both in the sporadic and inherited forms. We have seen the development of the first mouse models that accurately recapitulate features of the human disease. Several landmark clinical trials in both resectable and metastatic pancreatic cancer have been completed, raising new questions about the standard of care in this disease. Finally, the era of targeted biologic therapies has engendered new excitement about the prospects of more rapid progress in understanding and successfully treating this dreadful disease. Therefore, it is an appropriate time to review these important advances and outline areas of controversy and question in pancreatic cancer biology and treatment.




Pancreatic Cancer

Molecular Pathology of Gynecologic Cancer

Molecular Pathology of Gynecologic Cancer focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. The volume begins with an explication of the editors’ hypothesis that cancer is mainly a disease of the cell cycle, based on the deregulation of the physiological process of cell reproduction. The following eleven chapters focus on specific issues in gynecologic cancers, including: a proposed model of ovarian serous carcinogenesis, molecular markers for ovarian epithelial cancer, an overview of the pathology of endometrial cancer, molecular genetic aspects of endometrial carcinoma and cervical cancer, a natural history of Human Papilloma Virus (HPV) as it relates to cervical cancer, and hereditary issues in gynecologic cancers. The concluding chapter proposes and outlines a holistic approach to the treatment of female cancer patients. This new volume in Humana’s Current Clinical Oncology™ series will be necessary reading for clinicians and experimental researchers alike.



Molecular Pathology of Gynecologic Cancer

Handbook of Cancer Survivorship

Description: The Handbook on Cancer Survivorship responds to the diverse needs of survivors and their support communities by comprehensively addressing the major issues in the field, from the burden of survivorship to secondary prevention. Editor Michael Feuerstein, himself a cancer survivor, and sixty other top scientist-practitioners analyze in depth how survivors meet and manage the challenges of life after cancer, and what clinicians, researchers, and public health systems can do to ease the transition.



Handbook of Cancer Survivorship

Gene Therapy of Cancer Second Edition

The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific basis of gene therapy using immune, oncogene, antisense, pro-drug activating, and drug resistance gene targets, while other chapters discuss therapeutic approaches and clinical applications. This book is a valuable reference for anyone needing to stay abreast of the latest advances in gene therapy treatment for cancer.

Key Features
* Provides in-depth description of targeted systems and treatment strategies
* Explains the underlying cancer biology necessary for understanding a given therapeutic approach
* Extensively covers immune therapeutics of vaccines, cytokines, and peptide-induced responses
* Presents translational focus with emphasis on requirements for clinical implementation
* Incorporates detailed illustrations of vectors and therapeutic approaches ideal for classroom presentations and general reference



Gene Therapy of Cancer Second Edition

Fluoropyrimidine in Cancer Therapy

Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.


Fluoropyrimidine in Cancer Therapy

Complementary Oncology Adjunctive Methods in the Treatment of Cancer

Complementary Oncology is an excellent and open minded exploration of treatment options from a conventional medicine point of view. Even though this book is written by German doctors and researchers engaged in providing conventional care, the discussion is primarily on complementary treatment options and exhibits little or no bias.

Research and potential of many aspects such as exercise, nutrition, psychology, thermography, and many other treatments is well presented (although a bit scientific at times).

Care like proteolytic enzymes apparently is so common in Germany that it isn't even discussed, it's just assumed the patient will include them in their care (they are listed in the back as part of each care plan).

This book isn't for the average cancer patient. However if you have a scientific education and an interest in solid research of topics typically not mentioned or considered by American doctors then this is an excellent book to read. If you are a patient interested in obtaining the best care without bias or a caregiver that desires to be well educated then this book should be a "must have".



Complementary Oncology Adjunctive Methods in the Treatment of Cancer

Chemoradiation in Cancer Therapy

Internationally recognized experts in cancer biology and clinical research review the present status of the multimodality approach to the management of solid tumors and speculate on possible future strategies for chemoradiation therapy.

Chemoradiation in Cancer Therapy (Cancer Drug Discovery and Development)
By

* Publisher: Humana Press
* Number Of Pages: 432
* Publication Date: 2002-12-04
* Sales Rank: 2410289
* ISBN / ASIN: 158829028X
* EAN: 9781588290281
* Binding: Hardcover
* Manufacturer: Humana Press
* Studio: Humana Press
* Average Rating:
* Total Reviews:

Book Description:

Internationally recognized experts in cancer biology and clinical research review the present status of the multimodality approach to the management of solid tumors and speculate on possible future strategies for chemoradiation therapy. The authors detail applications of combined modality therapy in lung, esophageal, breast, gastric, pancreatic, colon, and rectal cancers. They also show how radiation interacts with such chemotherapeutic agents as the platinum complexes, taxanes, and gemcitabine in the treatment of malignant gliomas, and head and neck cancer. A review of how to integrate new specific molecular targeted agents into multimodality therapy in the future.



Chemoradiation in Cancer Therapy

Cancer Drug Resistance

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.


Cancer Drug Resistance

Breast Cancer Genes and the Gendering of Knowledge

The book examines the social and cultural context of new genetic knowledge associated with breast cancer. It looks at how this knowledge and technologies are used and received in two contrasting social arenas--cancer genetic clinics and a breast cancer research charity.


Breast Cancer Genes and the Gendering of Knowledge

Asbestos Selected Cancers 1,2

In conjunction with drafting comprehensive legislation concerning compensation for health effects related to asbestos exposure (the Fairness in Asbestos Injury Act), the Senate Committee on the Judiciary directed the Institute of Medicine to assemble the Committee on Asbestos: Selected Health Effects. This committee was charged with addressing whether asbestos exposure is causally related to adverse health consequences in addition to asbestosis, mesothelioma, and lung cancer. Asbestos: Selected Cancers presents the committee's comprehensive distillation of the peer-reviewed scientific and medical literature regarding association between asbestos and colorectal, laryngeal, esophageal, pharyngeal, and stomach cancers.


Asbestos Selected Cancers 1

Asbestos Selected Cancers 2

Apoptosis Senescence and Cancer

Apoptosis, Senescence and Cancer provides insight into established practices and research into apoptosis and senescence by thoroughly examining novel and emerging techniques and research in the fields of cell death pathways, senescence growth arrest, drugs and resistance, DNA damage response, and other topics which still hold mysteries for researchers.

The volume is divided into six easy to follow sections. The first is Apoptosis and Alternative Modes of Cell Death, followed by chapters on Telomeres and Telomerase, Senescence, Genomic Instability and Tumorigenesis. The third part covers DNA Damage Response, Signaling Pathways and Tumorigenesis, while the fourth delves into Resistance and Sensitization. The book concludes with Established Cancer Therapies and a section which looks toward the future with Recent and Developing Cancer Therapies.

In total, this volume provides basic scientists and clinicians with a deeper and more complete understanding of the cellular responses of malignancies which may determine the effectiveness of treatment, both in the initial stages of the disease as well as in disease recurrence.



Apoptosis Senescence and Cancer

Antiangiogenic Agents in Cancer Therapy

Beverly Teicher and a panel of distinguished investigators survey the state-of-the-art of antiangiogenesis research from the lab bench to clinical trials. Timely and authoritative, the contributors summarize our current understanding of tumor growth and its dependence on vascular development, as well as the present status of antiangiogenic agents in preclinical and clinical development. In addition, the book also examines what is known about the mechanisms by which these therapeutic agents interfere with tumor vasculature and grapples with the problem of establishing criteria by which to assess their clinical efficacy. Antiangiogenic Agents in Cancer Therapy offers a unique cutting-edge compendium of antiangiogenic research, taking stock of what has been accomplished , where the experimental therapeutics of antiangiogenic agents is going, and the continuing evolution of their role in cancer treatment and novel drug development.


Antiangiogenic Agents in Cancer Therapy

Alison The Cancer Handbook

Providing a comprehensive overview of scientific and clinical information in all major areas of cancer biology and medicine, The Cancer Handbook stands out from existing oncology textbooks and reference works in that it bridges the gap between the molecular biology of cancer and clinical diagnosis and treatment.

Covering a wide range of subjects - from basic cell biology to the systemic oncology of all major organs and tissues - the content of The Cancer Handbook has been organised into six major sections:

The Molecular Basis of Cell and Tissue Organisation
The Causation and Prevention of Cancer
Diagnostic Imaging and Image-Guided Intervention
Systemic Oncology
Pre-Clinical Models for Human Cancer
The Treatment of Human Cancer

It is an indispensable resource for medical and life science students, and all scientists, clinicians and researchers working in the cancer field and related biomedical areas.


Alison The Cancer Handbook

Advances in Radiation Oncology in Lung Cancer

Although decades of laboratory and clinical research have led to incremental improvement in treatment outcome, lung cancer remains one of the most deadly diseases. This volume is unique in being devoted solely to the radiation oncology of lung cancer, and will be of great value to all who are involved in the diagnosis and treatment of the disease. Both non-small cell and small cell lung cancer are considered in detail. Current state-of-the-art treatment strategies and novel approaches that promise further improvements in outcome are explained and evaluated, with the aid of high-quality illustrations. Treatment-related toxicity is discussed, and further individual chapters focus on topics such as quality of life studies, prognostic factors and pitfalls in the design and analysis of clinical trials.
If you look at the map of the world and check the incidence rates of cancer, you will find lung cancer as one of the major health problems worldwide. This is irrespective of sex and age, health care systems and current media reports. It is simply a fact that we sometimes forget, but it always comes again as a reminder with every new patient worldwide. This burden is present for decades and although there seems to be stagnation in males, plateau is not reached in females yet. Even then, we would still have to deal with thousands of patients suffering from the deadly disease. And we deal with it with radiation therapy, a treatment modality being now older than one-hundred years. During that period we have learnt how to fractionate the dose and observe the effects both on tumors and normal tissues. We have also learnt how to combine radiation therapy with other treatment modalities. With the time, we became increasingly capable of documenting dose distribution and to build on computerised-driven technologies to image, verify and record. We also became capable of concentrating on progressively smaller and smaller constituents; from the whole body to organs and tissues and from them to cells and molecules. We use radiation biology and molecular oncology to provide necessary framework for the science of radiation oncology in lung cancer.
And this book is about it; what had been done and what is going on. But much more than that, it is a book of what we have learnt from the past and how successfully we should incorporate it in our future endeavours, all having the same aim, better radiation oncology of lung cancer patients.


Advances in Radiation Oncology in Lung Cancer